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XENICAL is an oral prescription weight loss medication used to help obese people lose weight and keep this weight off. XENICAL works in your intestines, where it blocks some of the fat you eat from being absorbed. This undigested fat is then eliminated in your bowel movements. XENICAL should be used together with a reduced-calorie diet that your doctor will recommend.

Excess weight has been proven to contribute to an increased risk of developing many medical problems, including high blood pressure, high cholesterol, heart disease, and diabetes. The consumption of excess fatty food and calories plays a significant role in the development of excess weight. While fat is an important component of a balanced diet, the consumption of excess fat contributes to excess body weight, since fat provides twice the number of calories per gram of weight as carbohydrates and protein. Reduction of dietary fat intake is one potential way of losing weight.

How does XENICAL work?

If you eat an excess amount of fat or calories, the excess is stored as fat by the body resulting in weight gain. When you eat fat, your body breaks it down into its simplest components so that it can be absorbed. Enzymes in your intestinal tract, called lipases, help digest (or breakdown) fat. When you take XENICAL with meals, XENICAL attaches to the lipases and blocks them from breaking down some of the fat you have eaten. The undigested fat cannot be absorbed and is eliminated in your bowel movements. By working this way, XENICAL helps block about 30% of the fat eaten in food from being absorbed by your body.

Following one year of treatment, XENICAL in combination with diet was shown to be more effective in reducing weight than diet alone. In most cases, weight loss was gradual. Patients treated with XENICAL and a reduced-calorie diet for one year lost an average of 13.4 pounds while those on a reduced-calorie diet alone lost 5.8 pounds.

Who should use XENICAL?

A weight loss program that includes a reduced-calorie diet and appropriate physical activity may be adequate in some patients. You should discuss with your doctor or other health care provider whether XENICAL should be added to such a program.

XENICAL may be right for you if you are considerably overweight (at least 30% above ideal weight or a body mass index of 30 or greater). XENICAL may also be right for you if you are overweight (at least 20% above ideal weight or a body mass index of 27 or greater) and also have other risk factors such as high blood pressure, high cholesterol, heart disease, or diabetes.

How to determine your body mass index (BMI):

The chart below illustrates BMI according to a variety of weights and heights. The BMI is calculated by dividing your weight in kilograms by your height in meters squared. To use this chart:

Find the height closest to your height in the left-hand column.

Then move across the top row to find the weight closest to your weight.

The number where these two meet is your BMI. (For example, a person who weighs 180 lbs and is 5'5" would have a BMI of 30.)

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Frequently Asked Questions About Weight Loss And Diets


If you're on a diet, or considering going on one, you're in luck. We've put together ten of the most frequently asked questions about diets and weight loss and compiled them here. Enjoy!

1. How much should I weigh? Your doctor can answer that question most accurately. More important than how much you weigh is your body/mass index, which measures your height against your weight.

2. What's the best diet for losing weight? Any diet that provides all the nutrition that you need for health, and in addition, provides fewer calories than your body burns regularly.

3. How can I keep off the weight that I lose? If you lose weight gradually and re-educate both yourself and your body about food, you'll have a good start. The secret to keeping weight off is to balance your energy needs with your food intake. Eat enough calories to supply your body's energy needs, but not so many that your body stores the excess as fat.

4. What's the story with obesity and diabetes? Obesity increases the risks of a number of chronic health conditions, and diabetes is one of them. People who are more than ten percent overweight increase their risk of developing type 2 diabetes substantially.

5. How do I decrease my intake of sugar? Obviously, you can decrease your intake of sugar by cutting out sweets and refined snacks, but you should also watch out for 'hidden' sugars. Check ingredients. High fructose corn syrup and sucrose are both simple sugars that add lots of calories and little nutrition.

Based on pooled analysis in a subpopulation of elderly obese patients, the data suggest that Xenical is effective for weight loss in this population. The weight loss in obese elderly also resulted in improvements in many of the serious health risks associated with obesity. READ MORE

Unlike other obesity drugs, Xenical prevents enzymes in the gastrointestinal tract from breaking down dietary fats into smaller molecules that can be absorbed by the body. Absorption of fat is decreased by about 30 percent. Since undigested triglycerides are not absorbed, the reduced caloric intake may have a positive effect on weight control. READ MORE


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